OncoMed Pharmaceuticals, Inc.  

Careers at OncoMed

  • OncoMed, a pioneer and leader in the development of novel cancer therapies directed toward tumor initiating cells, also known as “cancer stem cells”, fosters a culture of innovation as the company strives to provide significant alternatives for the treatment of cancer.

    Headquartered in Redwood City, California, our employees bring a passionate dedication to the advancement of novel treatments for patients with cancer.

Open Positions:

Research Assistant, Translational Medicine


Job Summary We are looking for a highly motivated researcher that enjoys working in a fast paced work environment. The successful candidate will play an essential role in OncoMed’s Translational Medicine Group working on immunohistochemistry (IHC) based predictive biomarker studies in support of OncoMed’s clinical pipeline. The candidate will report to the Director, Translational Medicine.

  • IHC staining, both manual and automated, on pre-clinical, non-clinical and clinical samples
  • Develop novel IHC assays using internally generated as well as commercially available antibodies
  • Imaging of tissue sections using automated microscopy, database entry, and manual and automated image analysis
  • Tissue sectioning (paraffin and frozen), and basic histology techniques

  • Degree in Biological Sciences or related discipline with at least 2 years pharmaceutical industry experience
  • Experience in histology, including tissue sample preparation, sectioning, special stains and immunohistochemistry is required
  • Experience in the application of biomarkers towards oncology and immuno-oncology drug development is preferred
  • Familiarity with tumor pathology, cancer biology and image analysis is preferred
  • Excellent skills in written and oral communication are required
  • Works well and thrives in a collaborative matrix environment

Submit CV/Resume

Senior Manager / Associate Director, Project Management


Job Summary This position reports to the Sr Director Project Management. The successful candidate will manage cross-functional teams to establish product development plans/goals and to accomplish those goals in a timely manner. Assist teams in identifying critical hurdles faced in development programs and devising strategies to best address those challenges. Ensure that senior management is aware of program progress, issues, and key risks in order to best manage the corporate portfolio. Coordinate with internal groups, consultants and others as necessary to enhance goal achievement and regulatory filings

  • Direct project teams to develop sound and thorough product development plans (significant tasks, key assumptions, milestones and deliverables), and assist in managing the teams to implement the project with high quality standards according to approved project plan and timelines
  • Track project team activities to ensure progress against plan and the appropriate resources and priorities are established to keep programs on track
  • Identify and highlight critical decision points, events and milestones
  • Schedule, facilitate and document project team meetings and ad-hoc project meetings
  • Liaise with Finance regarding overall Development timelines and progress against budget baseline. Assess resource allocations and demand as needed
  • Liaise with Manufacturing and Supply Chain regarding enrollment projections and drug demand; highlighting significant shifts in project plans against baseline assumptions
  • Assist in implementing and refining a successful product development process, including identification of key decision points, navigating the decision-making matrices, highlighting risks/benefits associated with critical decision options, and support the prioritization and portfolio management activities
  • Communicate changes to project plans in a proactive and clear manner
  • Support the development and tracking of project goals and corporate goals
  • Serve as focal point for product development information. Keep central records for project plans, meeting minutes, and key decisions

  • Minimum of a B.S, in a related scientific discipline preferred. (Masters degree in business or in a relevant scientific discipline a plus)
  • Minimum of five years pharmaceutical/biotechnology experience in some area of product development with at least 2-5 years of experience in direct project management
  • Good general understanding of the Product Development life-cycle from IND through all development stages (P1, P2, P3)
  • Candidate must have sound understanding of the nuances of biotech product development activities (domestic and foreign), and of multi-project planning and coordination
  • Superior organizational skills, including established success in driving teams to complete follow-through
  • Excellent verbal and written communication skills. Must be able to communicate effectively at all levels of the organization
  • Strong ability to lead project team through complex subject matter, with ability to drive team to a decision and hold the team accountable for commitments
  • Proven track record of successfully working in cross-functional teams and projects
  • Proven track record or using and implementing project management tools which are both detailed and comprehensive and tailored to the specific needs of your project team and senior management
  • Must be team oriented, proactive, flexible, and be able to multi-task
  • Some knowledge of QA/QC, Regulatory, GCP, and GMP principles desirable
  • Must have a high proficiency in MS project and be able to create and update gantt charts and generate reports
  • Must have proficiency in Microsoft excel and PowerPoint

Submit CV/Resume

Clinical Finance Director


Job Summary Lead and manage the Company’s clinical finance planning, accruals, strategic analysis, including development of annual clinical budgets, quarterly forecasts and long-range clinical financial plans. This includes development of a bottom-up budget for all clinical studies and required CMC/preclinical activities to align with the Company’s corporate objectives. Work directly with VP Finance, present to senior management recommendations of business and clinical plans from financial perspectives.

Clinical FP&A Responsibilities:
  • Prepare clinical operating plan (with VP Finance and CFO)
  • Implement clinical budgeting, financial forecasting, operating plan and modeling tools
  • Prepare clinical monthly budget vs. actual reports and variance rationalizations for management, department heads and project teams
  • Support management and department heads in both the budgeting process and with clinical study and manufacturing budgets
  • Assist with the monthly management reporting
  • Continuously track cost performance and provide updates to department and team leaders on current financial performance
  • Perform ad hoc analyses as requested by management
  • Manage vendor contract reconciliations and invoice, PO and billing issue resolutions
  • Develop clinical financial models and analyses to support strategic initiatives
  • Implement and work with a business intelligence tool and dashboard reports
  • Monitor clinical performance indicators, highlighting trends and analyzing causes of unexpected variance

Clinical Operations Liaison Responsibilities:
  • Serve as the primary liaison between Finance and Clinical Operations groups
  • Manage monthly clinical trial accruals for all clinical studies, including account reconciliation, preparation of monthly adjusting entries to the general ledger, clinical account analysis as well as efficient interactions with external clinical research organization (CRO)
  • Monitor and track for financial reporting purposes all CRO spending, both actual and as compared to CRO budgets
  • Monitor and track for financial reporting purposes all Clinical Operations vendor spending, both actual and as compared to budgets
  • Collaborate with cross-functional leaders to enable analytics-driven clinical as well as financial decision making
  • Generate and monitor enrollment modeling scenarios and continuously evaluate the recruitment projections for improvements or triggers to support the implementation of action and/or contingency planning
  • Report project-level financial results using variance analysis and other analytical methods to explain underlying drivers such as patient enrollments
  • Develop and manage process for monthly management reporting packages
  • Design and implement internal controls, specifically over clinical trial accrual process, including identification of risks at each process, and design adequate controls to mitigate such risk
  • As requested, participate in training and staff meetings with Clinical Operations

  • Bachelor's degree in Accounting, Finance or related. MBA preferred
  • Minimum of 10 years’ experience in Clinical Financial and Planning and Analysis or Accounting
  • Life science (pharmaceutical, biotech, CMO or CRO) experience heavily preferred
  • Demonstrated history of resourcefulness, problem solving and ability to work both independently and collaboratively
  • Self-starter who can operate with autonomy and professionalism and seeks continuous improvement of business processes
  • Demonstrated ability to roll-up sleeves and work with team members in a hands-on management capacity
  • Must possess strong finance skills, analytical ability, and solid business acumen
  • Excellent verbal and written communication skills
  • Highest standards of accuracy and precision; highly organized
  • Advanced knowledge of Excel

Submit CV/Resume

Immunology Associate Scientist


Job Summary If you’re interested in working on cutting edge immunotherapy drug discovery, enjoy working in the biotech industry, and wish to contribute to the creation of new therapeutics that help patients, then OncoMed Pharmaceuticals is the place for you. The successful Associate Scientist in this position will be a key contributor for in vivo evaluation of anti-cancer drug candidates in our Immuno-Oncology group and will be involved in the discovery and testing of novel therapeutic agents. You’ll need to be both an effective team player and a strong individual contributor, flexible, able to handle multiple tasks, and eager to develop new techniques.

  • Ph.D. in cancer immunology and 0-2 years of post-doctoral training
  • Strong in vivo skills with mice including tumor implantation, various dosing and rodent surgery
  • Expertise on immunological assays including ELISPOT, T and NK cell Cytotoxicity, Treg/MDSC suppression assays as well as multi-parameter flow cytometry
  • Isolation of various cell populations from mice and ex vivo characterization
  • Ability to multitask and thrive in a fast-paced and challenging environment
  • Immunofluorescence imaging skill is a plus
  • Solid computer skills including Excel, PowerPoint, and GraphPad Prizm. Minimum of intermediate level is required
  • Motivation to learn new scientific techniques and to work in a team environment
  • Keeping up to date with current research field
  • Solid publication record demonstrating innovative research
  • Strong desire to work in a dynamic environment
  • Excellent oral/written communication and interpersonal skills

Submit CV/Resume